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- Zehra Ozfirat and Tahseen A Chowdhury.
- Department of Diabetes and Metabolism, The Royal London Hospital, Whitechapel, London, UK.
- Postgrad Med J. 2010 Jan 1; 86 (1011): 18-25; quiz 24.
AbstractType 2 diabetes is a major public health problem, accounting for significant premature mortality and morbidity. The growth in prevalence of the condition appears to be closely linked with obesity. Over the last 5 years, a number of large observational studies have suggested an association between the onset of type 2 diabetes and Vitamin D deficiency. Vitamin D has important effects on insulin action, and may impact on a number of pathways which may be of importance in the development of type 2 diabetes. This article reviews the evidence linking Vitamin D deficiency in the pathogenesis of type 2 diabetes, and suggests areas for urgent further research to determine whether Vitamin D replacement has a role in the prevention of type 2 diabetes.
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