• Rabia Ghafoor and Muhammad Irfan Anwar.
• Department of Dermatology, Jinnah Postgraduate Medical Centre, Karachi.
• J Coll Physicians Surg Pak. 2017 Apr 1; 27 (4): 200-202.

ObjectiveTo compare the mean Vitamin D level in patients with alopecia areata (AA) with age and gender controlled matched healthy controls.Study DesignCase-control study.Place And Duration Of StudyDermatology OPD, JPMC, from October 2014 to March 2015.MethodologyAll the patients diagnosed of alopecia areata by a trained dermatologist were selected. Controls were age and gender matched healthy volunteers. Venous blood was drawn and sent to hospital laboratory for 25 (OH) vitamin D by enzyme immunoassay method on chemical analyser. Data was recorded on SPSS version 16. Mann-Whitney test was applied to compare vitamin D levels of cases and controls. P-value <0.05 was taken as significant.ResultsThere are 30 cases of AA, and 30 age and gender matched controls. The mean age of our study group was 23.77 ±8.86 ng/dL in patients and 24.03 ±8.62 ng/dL in the control group. Fifteen (50%) patients presented between 3-12 months of onset of AA. Median (IQR) vitamin D level of cases was 13.5 (18.6) ng/dL and healthy controls was 22.5 (16.25) (p=0.001).ConclusionSerum Vitamin D levels were significantly lower in patients with alopecia areata compared to healthy controls.

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