• Preventive medicine · May 2012

    Review

    Improvement of the lipid profile with exercise in obese children: a systematic review.

    • Yolanda Escalante, Jose M Saavedra, Antonio García-Hermoso, and Ana M Domínguez.
    • Facultad de Ciencias del Deporte, AFIDES Research Group, Universidad de Extremadura, Avda. Universidad s/n, 10071-Cáceres, Spain. yescgon@unex.es
    • Prev Med. 2012 May 1; 54 (5): 293-301.

    ObjectiveThe objective of this systematic review was to assess the effectiveness of different physical exercise interventions on the lipid profile (high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglycerides (TG)) of obese children.MethodA computerized search was made of seven databases using keywords. Effect sizes (ES) and 95% confidence intervals were calculated, and the heterogeneity (I(2)) of the studies was estimated using Cochran's Q-statistic applied to the effect size means. The studies were grouped according to the intervention program-aerobic alone or combined (aerobic fitness, strength, and flexibility).ResultsSeven studies were selected for review as satisfying the inclusion criteria. Six were randomized controlled trials (n=318) and one was a controlled clinical trial (groups not randomly assigned) (n=38). The main cumulative evidence indicates that the programs based on aerobic exercise alone have a moderate (ES=-0.49; I²=87) and a large effect (ES=-0.55; I²=77) on LDL-C and TG concentrations, respectively; and the programs based on combined exercise have a moderate effect (ES=0.50; I²=0) on HDL-C concentration.ConclusionsThe programs based on aerobic exercise (60 min, 3 times/week, ≤75% maximum heart rate) improve the LDL-C and TG concentrations. Moreover, the programs based on combined exercise (≥60 min, >75% maximum heart rate) also improve the HDL-C concentration.Copyright © 2012 Elsevier Inc. All rights reserved.

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