• Ying-Dong Cui, Shu-Bin Hu, Bo Wu, Shi-Jun Li, Kui Xiang, Zhao-Lin Liao, Hui-Ping Zhang, Chang-Hong Zhu, and Meng Rao.
• Department of Urology, Enshi Tujia and Miao Autonomous Prefecture nationality Hospital, Enshi, Hubei, China.
• Afr Health Sci. 2017 Sep 1; 17 (3): 603-613.

ObjectivesWe recommend a new kind of spray made from eight kinds of traditional Chinese medicine, we aimed to investigate the safety and clinical efficacy of combined traditional Chinese medicine spray (TCMS) with premature ejaculation desensitization therapy (PEDT) for the treatment of primary premature ejaculation (PPE).MethodsA total of 90 patients with PPE were randomly assigned to receive TCMS, PEDT monotherapy or TCMS plus PEDT combination therapy for 6 weeks. Intravaginal ejaculation latency time (IELT) and Chinese index of sexual function for premature ejaculation (CIPE-5) were measured to evaluate the effect of each treatment.ResultsEighty six (86) participants completed the study voluntarily. Both IELT and CIPE-5 in these three groups increased after treatment when compared with baseline levels (p< 0.01). IELT and CIPE-5 after treatment in TCMS plus PEDT group were significantly higher than those in the other two groups (both p <0.05). Additionally, clinical efficacy in TCMS plus PEDT group (89.7%) was significantly higher than in TCMS (65.5%) and PEDT group (67.9%) (p< 0.01).ConclusionThe self-made TCMS was safe and effective for the treatment of PPE, a combination of TCMS and PEDT therapy was more effective than the TCMS or PEDT monotherapy.

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