• Qionghui Huang, Aihong Luo, Lijuan Jiang, Yan Zhou, Yanting Yang, Qiong Liu, and Chunfang Zhang.
• Central sterile supply department, Xiangya Hospital, Central South University 410008.
• Afr Health Sci. 2019 Mar 1; 19 (1): 1441-1448.

BackgroundIn recent times, biosyntheses of metal nanoparticles were used for several life rescue applications. In this study, Dillenia indica leaf aqueous extract was utilized for the synthesis of gold nanoparticles.ObjectiveTo test anti-microbial properties of biologically fabricated gold nanoparticles.MethodsGold nanoparticles were efficiently prepared by making use of aqueous leaf extract of Dillenia indica. The excitation of formed AuNPs was confirmed using UV-Vis spectrophotometer. In particular, absorption spectra of AuNPs exhibited a well-defined SPR band centered at around 530 nm.ResultsThe high-resolution Scanning Electron Microscope (SEM) results of the obtained AuNPs confirmed the formation of particles with a size range of 5-50 nm. The ultra-high resolution TEM (UHRTEM) images displayed clear lattice fringes on the particle surfaces. Single crystalline nature of the biosynthesized AuNPs was represented by means of selected-area electron diffraction pattern.ConclusionThe antibacterial activity of AuNPs revealed significant activity towards both gram negative and gram positive bacteria signifying their potential disinfection related applications in medicine and biology.

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