• Neurosurgery · Feb 2020

    Review

    Pharmacological therapy after acute cervical spinal cord injury.

    • M N Hadley, B C Walters, P A Grabb, N M Oyesiku, G J Przybylski, D K Resnick, and T C Ryken.
    • Neurosurgery. 2020 Feb 3; 50 (3 Suppl): S63-72.

    CorticosteroidsStandardsThere is insufficient evidence to support treatment standards.GuidelinesThere is insufficient evidence to support treatment guidelines.OptionsTreatment with methylprednisolone for either 24 or 48 hours is recommended as an option in the treatment of patients with acute spinal cord injuries that should be undertaken only with the knowledge that the evidence suggesting harmful side effects is more consistent than any suggestion of clinical benefit. GM-1 GANGLIOSIDE:StandardsThere is insufficient evidence to support treatment standards.GuidelinesThere is insufficient evidence to support treatment guidelines.OptionsTreatment of patients with acute spinal cord injuries with GM-1 ganglioside is recommended as an option without demonstrated clinical benefit.

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