-
Emerg Med Australas · Jun 2022
Venous blood for the analysis of acid-base status in a model of septic shock.
- Matthew J Maiden, Jonathan D Fraser, and Mark E Finnis.
- Intensive Care Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
- Emerg Med Australas. 2022 Jun 1; 34 (3): 456-458.
ObjectiveTo determine the relationship between arterial and venous acid-base status in a model of septic shock.MethodsPaired samples (n = 435) of arterial and femoral venous blood from 57 sheep (47 septic, 10 non-septic) managed with protocol-guided ventilation, sedation, parenteral fluids and inotropic support.ResultsThe arterial-venous difference in acid-base parameters was similar with and without sepsis. There was a consistent arterio-venous relationship for metabolic (pH, lactate, bicarbonate, base excess), but not respiratory parameters (partial pressures of oxygen, carbon dioxide, and haemoglobin-oxygen saturation), independent of sepsis.ConclusionsVenous blood provides a reliable measure of metabolic but not respiratory disturbance.© 2022 The Authors. Emergency Medicine Australasia published by John Wiley & Sons Australia, Ltd on behalf of Australasian College for Emergency Medicine.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..