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- Takashi Kitade, Noriyuki Horiki, Masaki Katsurahara, Toshiaki Totoki, Tetsuro Harada, Shunsuke Tano, Reiko Yamada, Yasuhiko Hamada, Hiroyuki Inoue, Kyosuke Tanaka, Esteban C Gabazza, Hiroyuki Hayashi, Masanori Tanaka, and Yoshiyuki Takei.
- Department of Endoscopy, Mie University Hospital, Japan.
- Intern. Med. 2015 Jan 1; 54 (11): 1343-7.
AbstractA 66-year-old Japanese man consulted our institution due to paroxysmal and repetitive bouts of fever and abdominal pain that had persisted for more than one week. Capsule and double-balloon endoscopy (DBE) showed petal-shaped mucosal redness with white hemming in the jejunum and ileum, and histopathology of the biopsy specimens revealed villous atrophy and cryptitis with extensive severe neutrophil infiltration. A genetic examination disclosed compound heterozygous MEFV mutations (E84K, P369S), and familial Mediterranean fever was diagnosed. Treatment with colchicine and infliximab was very effective in inducing the complete disappearance of symptoms and normalization of the endoscopic findings. To the best of our knowledge, this is the first report to describe the findings of small intestinal endoscopic images obtained using capsule and DBE.
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