• J Res Med Sci · Jan 2021

    How is insulin-like growth factor-1 correlated with retinopathy of prematurity?

    • Nahid Jafari, Arezoo Karimi Moghadam, Naeeme Taslimi Taleghani, Neda Hosseini Nezhad, Nima Motamed, and Ahmad Jalilvand.
    • Department of Neonatology and Perinatology, Zanjan University of Medical Science, Zanjan, Iran.
    • J Res Med Sci. 2021 Jan 1; 26: 111.

    BackgroundEvaluation of insulin-like growth factor-1 (IGF-1) association with retinopathy of prematurity (ROP) is our object.Materials And MethodsThis study was conducted on IGF-1 levels of 40 neonates <34 weeks gestational age and 2000 g at 1st week and 4-6 weeks after birth. All participants were evaluated for ROP after 31 weeks of gestation.ResultsIGF-1 levels showed a significant difference between neonates ≤1500 and 1500-2000 g (1 and 4-6 weeks, P = 0.008, P = 0.039, respectively). No significant association was found between IGF-1 and ROP.ConclusionFinding a meaningful association between IGF-1 and ROP requires consideration of factors affecting the IGF-1.Copyright: © 2021 Journal of Research in Medical Sciences.

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