• Mitra Ranjbar, Mohammad Hadi Karbalaie Niya, Maryam Roham, Nader Rezaie, Mahdi Yadollahzadeh, Mohsen Farrokhpour, Mehdi Azimi, Nima Motamed, Dhayaneethie Perumal, TameshkelFahimeh SafarnezhadFSGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran., Farahnaz Dadras, Nahid Hashemi Madani, Behrooz Ghanbari, Amirhossein Faraji, Mehdi Nikkhah, Shahrzad Rahmani, Fatemah Golgiri, Seyed Yadollah Emadi, Rowshanak Abbasi, Iman Mohseni, Mohammad Reza Babaei, Ramin Eskandari, Manizhe Ataee, Mahshid Panahi, Farhad Zamani, MakianiMahin JamshidiMJDepartment of Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.Antimicrobial Resistant Research Center, Iran University of Medical Sciences, Tehran, Iran., and Azadeh Laali.
• Department of Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.
• J Res Med Sci. 2021 Jan 1; 26: 112112.

BackgroundDue to widespread of coronavirus disease 2019 (COVID-19) infection, identification of its risk factors and clinical characteristics are important. The aim of the present study was to assess Vitamin D levels in individuals with severe acute respiratory syndrome coronavirus-19 infection and to report on its potential as a predictive marker.Materials And MethodsAll patients, diagnosed with COVID-19 infection from February 16 to March 21, 2020, and referred to Firoozgar Hospital, Tehran, Iran, were enrolled in this study. Vitamin D analysis was undertaken on patient serum samples using a commercial kit (Pars Azmoon Co., Tehran, Iran). SPSS v. 22 was used for statistical analysis.ResultsVitamin D serum concentration was analyzed in a total of 317 patients whose mean age ± standard deviation was 62.05 ± 15 years and with 62.5% being male. A significant association of Vitamin D level and death was observed. Higher levels of serum Vitamin D had protection against death (odds ratio = 0.955 [95% confidence interval = 0.923-0.988], P = 0.008).ConclusionAs a preliminary study in the Iranian population who suffered COVID-19 disease, we identified that Vitamin D deficiency was associated with a higher death rate and intensive care unit admission.Copyright: © 2021 Journal of Research in Medical Sciences.

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