• Mohammad Ali Ashraf, Nasim Shokouhi, Elham Shirali, Fateme Davari-Tanha, Kiana Shirani, Omeed Memar, Alireza Kamalipour, Ayein Azarnoush, Avin Mabadi, Adele Ossareh, Milad Sanginabadi, AzadTalat MokhtariTMThe National Influenza Centre, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Leila Aghaghazvini, Sara Ghaderkhani, Tahereh Poordast, Alieh Pourdast, and Pershang Nazemi.
• Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
• J Res Med Sci. 2021 Jan 1; 26: 114.

BackgroundThere is a growing need for information regarding the recent coronavirus disease of 2019 (COVID-19). We present a comprehensive report of COVID-19 patients in Iran.Materials And MethodsOne hundred hospitalized patients with COVID-19 were studied. Data on potential source of exposure, demographic, clinical, and paraclinical features, therapy outcome, and postdischarge follow-up were analyzed.ResultsThe median age of the patients was 58 years, and the majority of the patients (72.7%) were above 50 years of age. Fever was present in 45.2% of the patients on admission. The most common clinical symptoms were shortness of breath (74%) and cough (68%). Most patients had elevated C-reactive protein (92.3%), elevated erythrocyte sedimentation rate (82.9%), and lymphocytopenia (74.2%) on admission. Lower lobes of the lung were most commonly involved, and ground-glass opacity (81.8%) was the most frequent finding in computed tomography scans. The administration of hydroxychloroquine improved the clinical outcome of the patients. Lopinavir/ritonavir was efficacious at younger ages. Of the 70 discharged patients, 40% had symptom aggravation, 8.6% were readmitted to the hospital, and three patients (4.3%) died.ConclusionThis report demonstrates a heterogeneous nature of clinical manifestations in patients affected with COVID19. The most common presenting symptoms are nonspecific, so attention should be made on broader testing, especially in age groups with the greatest risk and younger individuals who can serve as carriers of the disease. Hydroxychloroquine and lopinavir/ritonavir (in younger age group) can be potential treatment options. Finally, patients discharged from the hospital should be followed up because of potential symptom aggravation.Copyright: © 2021 Journal of Research in Medical Sciences.

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