• Volkan Hanci, Mustafa Aydin, Bülent Serhan Yurtlu, Hilal Ayoğlu, Rahsan Dilek Okyay, Ebru Taş, Gülay Erdoğan, Keziban Aydoğan, and Isil Ozkoçak Turan.
• Department of Anesthesiology and Reanimation, School of Medicine, Zonguldak Karaelmas University, Turkey. vhanci@gmail.com
• Kaohsiung J Med Sci. 2010 Sep 1;26(9):470-7.

AbstractThe present study compared the effects of anesthesia induction with sevoflurane and propofol on hemodynamics, P-wave dispersion (Pwd), QT interval and corrected QT (QTc) interval. A total of 72 adult patients were included in this prospective study. All patients had control electrocardiograms (ECGs) before anesthesia induction. Anesthesia was induced with sevoflurane inhalation or intravenous propofol. Electrocardiography for all patients was performed during the 1(st) and 3(rd) minutes of induction, 3 minutes after administration of muscle relaxant, and at 5 minutes and 10 minutes after intubation. Pwd and QT intervals were measured on all ECGs. QTc intervals were determined using the Bazett formula. There was no significant difference in Pwd and QT and QTc intervals on control ECGs. In the sevoflurane group, except for control ECGs, Pwd and QTc interval on all ECGs were significantly longer than those in the propofol group (p < 0.05). We conclude that propofol should be used for anesthesia induction in patients with a predisposition to preoperative arrhythmias, and in those whose Pwd and QTc durations are prolonged on preoperative ECGs.Copyright © 2010 Elsevier. Published by Elsevier B.V. All rights reserved.

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