• Filippo Migliorini, Andrea Pintore, Gianluca Vecchio, Francesco Oliva, Frank Hildebrand, and Nicola Maffulli.
• Department of Orthopaedics, University Clinic Aachen, RWTH Aachen University Clinic, 52064 Aachen, Germany.
• Br. Med. Bull. 2022 Sep 22; 143 (1): 57-68.

IntroductionSeveral strategies are available for posterior cruciate ligament (PCL) reconstruction.Source Of DataRecently published literature in PubMed, Google Scholar and Embase databases.Areas Of AgreementThe Ligament Advanced Reinforcement System (LARS) is a scaffold type artificial ligament, which has been widely used for ligament reconstruction of the knee.Areas Of ControversyCurrent evidence on the reliability and feasibility of LARS for primary isolated PCL reconstruction is limited.Growing PointsThe primary outcome of interest of the present work was to investigate the outcomes of PCL reconstruction using the LARS. The secondary outcome of interest was to compare the LARS versus four-strand hamstring tendon (4SHT) autograft for PCL reconstruction.Areas Timely For Developing ResearchLARS for primary isolated PCL reconstruction seems to be effective and safe, with results comparable to the 4SHT autograft.© The Author(s) 2022. Published by Oxford University Press.

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