• Sertac Yazici, Meylis Artykov, Hakan Bahadir Haberal, Turan Mammadaliyev, Ahmet Gudeloglu Br, and Cenk Yucel Bilen.
• Department of Urology, Hacettepe University School of Medicine, Ankara, Turkey.
• J Coll Physicians Surg Pak. 2022 May 1; 32 (5): 565-569.

ObjectiveTo compare perioperative outcomes of minimally invasive surgery for ≥5 cm and <5 cm adrenal lesions.Study DesignRetrospective cohort study.Place And Duration Of StudyHacettepe University School of Medicine, Ankara, Turkey, between October 2007 and September 2019.MethodologyData of 83 patients operated for adrenal lesions was collected retrospectively. Patients were categorized into two groups based on the size of the adrenal gland as <5 cm and ≥5 cm. The groups were compared in terms of perioperative outcomes.ResultsThe median age of the patients was 51 (41-60) years, with a female-to-male ratio of 27/56. The median follow-up period was 27 (11.5-91) months. Of 83 adrenal masses, 60 (72.3%) were in the <5 cm group and 23 (27.7%) were in the ≥5 cm group. Fifteen (18.1%) patients underwent adrenalectomy for lung cancer metastasis, whereas three (3.6%) for renal cell carcinoma metastasis. The overall rate of post-operative complications was 10.8%. Post-operative complication rates were similar in each group (p=0.433). Operation time was found to be significantly higher in patients with large adrenal masses (p=0.003).ConclusionMinimally invasive surgical techniques have the same perioperative results in the group with adrenal lesions ≥5 cm compared to <5 cm and may be safely employed in this group of patients.Key WordsLaparoscopy, Robotic assisted laparoscopy, Adrenalectomy, Metastasectomy, Adrenal gland neoplasms.

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