• Pardeep Kumar, Mudassir Hussain, Mehnaz Jabeen, Rehan Mohsin, Gauhar Sultan, and Altaf Hashmi.
• Department of Urology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan.
• J Coll Physicians Surg Pak. 2022 May 1; 32 (5): 627-631.

Objective To compare the drop in eGFR after nephron-sparing surgery in T1 and T2 renal tumours.Study Design Descriptive study.Place And Duration Of Study Department of Uro-oncology, Sindh Institute of Urology, and Transplantation Karachi, from March 2020 to March 2021.Methodology Retrospective data were collected for all patients who underwent nephron-sparing surgery between 2014 to 2019. Eighty-seven patients were divided into two groups based on the T stage of renal tumours (T1 ≤7 cm and T2 >7 cm). The outcomes of the two groups were compared such as eGFR, blood transfusion, hospital stay and complications.Results There was a higher drop in eGFR in T2 tumours when compared to T1 tumours at 1 year of follow-up. There were more perioperative complications, higher blood transfusions and longer hospital stays for T2 tumours.Conclusion Nephron sparing surgery for T2 renal tumours carries lower eGFR preservation, higher blood transfusions and complications when compared to T1 tumours. The indication for such extensive surgery should be individualized to specific contexts only.Key WordsAdenocarcinoma kidney, Nephrectomy, Glomerular filtration rate, Length of hospital stay, Blood transfusion.

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