• Postgrad Med J · Jun 2023

    Review

    Discovery of insulin 100 years on.

    • David Russell-Jones and Zosanglura Bawlchhim.
    • CEDAR, Royal Surrey County Hospital, Guildford, UK.
    • Postgrad Med J. 2023 Jun 30; 99 (1173): 661668661-668.

    AbstractThe discovery of insulin 100 years ago ranks among the greatest medical achievements ever. This sparked a revolution of scientific discovery and therapeutic intervention to treat people suffering with diabetes. A light was shone for other areas of medicine to illuminate what was possible with detailed scientific endeavour. There followed a range of firsts leading to the current time in which we now know more about this peptide hormone than almost any other protein in existence. This has allowed therapeutic advancement from a positon of knowledge leading to stunning innovation. This innovation is likely to lead to more physiological insulin replacement reducing the disease burden to individuals and society as whole.© The Author(s) 2022. Published by Oxford University Press on behalf of Postgraduate Medical Journal. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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