• Kuo-Wei Kao, Weiming Cheng, and Yi-Chin Chang.
• Division of Urology, Department of Surgery, Taipei City Hospital, Renai Branch, Taipei, Taiwan.
• Medicine (Baltimore). 2022 May 20; 101 (20): e29229e29229.

RationaleChondromas are benign tumors comprising cartilaginous tissue that commonly occur in the small bones of the hands and feet. Chondromas are extremely rare in extraskeletal soft tissues, and only six cases of bladder chondromas have been reported thus far.Patient ConcernsA 75-year-old woman presented with abdominal pain and urinary symptoms, including increased frequency and a weak stream.DiagnosisCystoscopy revealed a well-defined bladder mass over the anterior bladder wall. The pathology report showed neoplastic chondrocytes within the hyalinized and focal myxoid matrix, and immunopositivity for S-100, leading to the seventh known diagnosis of bladder chondroma.InterventionsThe tumor was endoscopically resected. The postoperative stay was uneventful, and 5 days later, the patient was discharged after the removal of the urinary catheter.OutcomesOne month after surgery, repeated cystoscopy showed no recurrence of the bladder tumor, and the patient reported improvement in urinary symptoms and relief of lower abdominal pain.LessonsChondromas of the urinary bladder can present as urinary symptoms and abdominal pain in older patients. Transurethral resection is the treatment of choice.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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