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- Waqas Shakir, Abdur-RehmanAbdur Rehman, FCPS Department of Neonatology, Children's Hospital and The Institute of Child Health, Multan, Pakistan., M Sohail Arshad, and Nazia Fatima.
- Waqas Shakir, FCPS (Pediatrics Medicine), Department of Neonatology, Children's Hospital and The Institute of Child Health, Multan, Pakistan.
- Pak J Med Sci. 2022 Mar 1; 38 (4Part-II): 883887883-887.
ObjectivesTo find out the burden of cardiovascular dysfunction and outcome among term newborns having birth asphyxia.MethodsThis prospective observational study was conducted at The Department of Neonatology, Children's Hospital and The Institute of Child Health, Multan from August 2020 to March 2021.A total of 171 term newborns having asphyxia were enrolled. Detailed history along with clinical and physical examination were done at the time of admission at Neonatal Intensive Care Unit (NICU). All neonates were followed up for duration of 14 days following birth. Echocardiographic patterns as well as electrocardiography grading were described among neonates with cardiovascular abnormalities.ResultsOut of a total of 171 neonates, there were 94 (55.0%) male and 77 (45.0%) female. Lowe segment cesarean section was the mode of delivery in 72 (42.1%) while normal vaginal delivery was noted in 99 (57.9%). Mean gestational age was noted to be 38.3±1.8 weeks. Mean birth weight was calculated to be 2574.10±122.30 grams. Cardiovascular dysfunction was noted among 60 (35.1%) neonates as exhibited by the use of inotropes while abnormal ECHO was observed in 52 (30.4%), abnormal ECG in 27 (15.8%) and elevated CK-MB in 31 (18.1%). A total of 29 (17.0%) asphyxiated neonates died while among 60 asphyxiated neonates with cardiovascular dysfunction, 23 (38.3%) died and all remaining survived and discharged (p<0.0001).ConclusionCardiovascular dysfunction among asphyxiated neonates was found to be in high proportion of cases. Cardiovascular dysfunction was noted to have significant association with poor outcome.Copyright: © Pakistan Journal of Medical Sciences.
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