• Pak J Med Sci · Mar 2022

    The effect of platelet rich plasma combined with celecoxib on knee function and pain in patients with knee osteoarthritis.

    • Mingjun Nie, Jianzhong Zhao, Guangcheng Zhang, Jiazhu Tang, Wei Zhu, and Qing Zhang.
    • Mingjun Nie, Department of Orthopedics, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, Jiangsu Province, P.R. China.
    • Pak J Med Sci. 2022 Mar 1; 38 (4Part-II): 796-800.

    ObjectivesTo analyze the immediate effect of platelet rich plasma, combined with celecoxib, on knee function and pain in patients with knee osteoarthritis.MethodsThe clinical data of 86 patients with knee osteoarthritis, treated in our hospital from January 2019 to January 2021, were analyzed retrospectively. According to the treatment records, patients were divided into a control group (n = 43, celecoxib) and a treatment group (n = 43, platelet rich plasma + celecoxib). The knee function, pain and clinical effect in the two groups were compared and analyzed using the Hospital for Special Surgery (HSS) knee score and the visual analog scale (VAS).ResultsThe treatment group had a higher HSS score, and a lower VAS score compared to the control group (P<0.05). The clinical efficacy in the treatment group was higher than that in the control group (95.35% and 72.09% respectively, P<0.05).ConclusionsPlatelet rich plasma combined with celecoxib can promote the recovery of knee function and reduce pain in patients with knee osteoarthritis. This treatment combination also has a high immediate clinical effectiveness but needs further evaluation to find out the long term effects.Copyright: © Pakistan Journal of Medical Sciences.

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