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- Mark Siobal.
- Respiratory Care Services, San Francisco General Hospital, NH GA-2, 1001 Potrero Avenue, San Francisco, CA 94110, USA. msiobal@sfghsom.ucsf.edu.
- Resp Care. 2004 Jun 1;49(6):640-52.
AbstractTwo prostacyclins (prostaglandin E(1) and prostaglandin I(2)) are potent vasodilators. Aerosolized prostacyclins reduce pulmonary artery pressure, improve right heart function, and increase arterial oxygenation by improving ventilation/perfusion matching. This report describes aerosolized prostacyclins and compares them to inhaled nitric oxide. I review the types of inhalable prostacyclins and their indications, evidence of efficacy, delivery, and adverse effects.
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