• Rev Assoc Med Bras (1992) · Apr 2022

    Relationship between the number of comorbidities, quality of life, and cardiac autonomic modulation in patients with coronary disease: a cross-sectional study.

    • Heloisa Balotari Valente, Vitor Eduardo Dos Santos Silva, Thamyres Rangel Mendes Barros, Franciele Marques Vanderlei, Maria Júlia Lopez Laurino, Ana Flavia Balotari Botta, Laís Manata Vanzella, Antonio Claudio Bongiovani, and VanderleiLuiz Carlos MarquesLCM0000-0002-1891-3153Universidade Estadual Paulista, School of Technology and Sciences - Presidente Prudente (SP), Brazil..
    • Universidade Estadual Paulista, School of Technology and Sciences - Presidente Prudente (SP), Brazil.
    • Rev Assoc Med Bras (1992). 2022 Apr 1; 68 (4): 450455450-455.

    ObjectiveThe aim of this study was to evaluate if there is a relationship between the number of comorbidities, autonomic modulation, and quality of life in patients diagnosed with coronary artery disease.MethodsA cross-sectional study was conducted at an outpatient rehabilitation center in Presidente Prudente-SP, Brazil. A total of 27 participants (65.33±9.23 years) diagnosed with coronary artery disease were assessed, from a cardiac rehabilitation program, independent of sex or age. The number of comorbidities was evaluated using the Self-Administered Comorbidity Questionnaire, and quality of life was evaluated using the Medical Outcome Study 36-Item Short Form Health Survey (SF-36) (eight domains: functional capacity, physical aspects, pain, general health status, vitality, social aspects, emotional aspects, and mental health). To evaluate the cardiac autonomic modulation, the heart rate was registered beat to beat using an heart rate monitor in the supine position during rest for 30 min. A total of 1000 RR intervals were considered to calculate linear (time domain: RMSSD, SDNN; frequency domain: LF, HF, LF/HF) and nonlinear indices (SD1, SD2, SD1/SD2) of heart rate variability.ResultsA negative correlation was observed between the aggregation of comorbidities and the pain domain of the SF-36 (r=-0.427; p=0.03). No significant correlations were observed between other variables (p>0.05).ConclusionThe number of comorbidities is inversely related to the pain domain of the SF-36, suggesting that a higher pain level is related to a higher number of comorbidities in coronary artery disease patients.

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