Revista da Associacao Medica Brasileira (1992)
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Long-acting depot formulations of somatostatin analogs, i.e., octreotide and lanreotide, are the first-line medical therapies for patients with acromegaly to whom surgery/radiotherapy cannot be performed or who have inadequate response. In this study, we aimed to evaluate the short-term local and systemic adverse reactions developed after the somatostatin analogs injections in the patients with acromegaly, in order to compare the side effects of somatostatin analogs injections. ⋯ This is the first prospective study that compared the severity of the injection-site pain by using a scoring scale, following the long-acting somatostatin analogs injections. We have shown that there was no significant association of the injection-site pain severity with the somatostatin analogs regimen nor the dose differences within each somatostatin analogs treatment.
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Rev Assoc Med Bras (1992) · Apr 2022
Observational StudyQuality of primary health care for quilombolas' Afro-descendant in Brazil: A cross-sectional study.
The aim of this study was to assess the quality of primary health care services through self-reports by caregivers of children and adolescents living in quilombola communities in Brazil. ⋯ The quality of primary health care has generally satisfactory values. However, as these results differ from most studies, more research should be conducted.
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Rev Assoc Med Bras (1992) · Apr 2022
Relationship between the number of comorbidities, quality of life, and cardiac autonomic modulation in patients with coronary disease: a cross-sectional study.
The aim of this study was to evaluate if there is a relationship between the number of comorbidities, autonomic modulation, and quality of life in patients diagnosed with coronary artery disease. ⋯ The number of comorbidities is inversely related to the pain domain of the SF-36, suggesting that a higher pain level is related to a higher number of comorbidities in coronary artery disease patients.
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Rev Assoc Med Bras (1992) · Apr 2022
Tumorigenic and immunological roles of Heat shock protein A2 in pancreatic cancer: a bioinformatics analysis.
Heat shock protein A2 has been reported to be tightly associated with tumorigenesis and tumor progression. This study aimed to determine the oncogenic and immunological roles of Heat shock protein A2 in pancreatic cancer by bioinformatics. ⋯ Heat shock protein A2 is upregulated in pancreatic cancer and is closely associated with tumor immunity and aggressive progression.
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Rev Assoc Med Bras (1992) · Apr 2022
Risk factors associated with infections in pregnant women with systemic lupus erythematosus.
The aim of this study was to analyze the occurrence and risk factors associated with infections during pregnancy in patients with systemic lupus erythematosus. ⋯ The study showed an increased chance of infections in pregnant women with systemic lupus erythematosus and it was associated with the use of prednisone.