• Khaled Ali, Mhd Baraa Habib, Ferial Alloush, and Mohamed A Yassin.
• Community Medicine Department, Hamad Medical Corporation, Doha, Qatar.
• Medicine (Baltimore). 2022 Jun 10; 101 (23): e29236e29236.

IntroductionAlthough it usually involves extranodal sites such as the gastrointestinal tract in more than 80% of cases, mantle cell lymphoma is considered a rare cause of gastrointestinal bleeding, especially severe and life-threatening bleeding.Patient ConcernA 60-year-old man with peptic ulcer disease, who presented with severe upper gastrointestinal (GI) bleeding and large gastric ulcer.DiagnosisPrimary gastric mantle cell lymphoma.InterventionsHe was treated conservatively with blood transfusion and started on Traneximic acid for 3 days. Then, the patient underwent urgent hemostatic radiotherapy.OutcomesThe patient became stable and kept in the hospital for monitoring with a definite diagnosis of stage IV Mantle cell lymphoma is made.ConclusionMantle cell lymphoma should be kept in mind when assessing massive upper GI bleeding, as an unusual cause of bleeding gastric ulcer, given that bleeding is an uncommon presenting feature of GI lymphoma.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

20 keywords...

hide…