• Đorđe Ilić, Aleksandra Ilić, Snežana Stojšić, Anastazija Stojšić-Milosavljević, Jelena Papović, Dragana Grković, Olivera Rankov, Aleksandra Milovančev, and Lazar Velicki.
• 1University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; 2Department of Obstetrics and Gynecology, Clinical Center of Vojvodina, Novi Sad, Serbia; 3Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia; 4Institute of Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia.
• Acta Clin Croat. 2021 Dec 1; 60 (4): 641-650.

AbstractThe study aimed to determine if the non-dipping pattern of blood pressure (BP) influences preterm delivery in gestational hypertension (GH), but also maternal clinical findings and birth weight. Sixty women with GH, i.e. 30 women with a dipping BP profile (control group) and 30 non-dippers (study group), were included in the study. Echocardiography was performed in all subjects, as well as ambulatory blood pressure monitoring (ABPM) during third trimester. ABPM was repeated 6-8 weeks after delivery. Thirteen women with preterm delivery were classified as non-dippers and only four as dippers (p=0.01). The average and peak systolic and diastolic night-time BP had negative linear correlation with birth weight (p<0.0005). Total vascular resistance (p<0.0005) and mass index (p=0.014) were significantly higher as compared with women with term delivery, while ejection fraction (EF) (p=0.007) and circumferential systolic velocity (p=0.042) were significantly reduced in the preterm delivery group. Multivariate binary logistic regression identified the average night-time systolic BP, left ventricular mass index and EF as independent predictors of preterm delivery. Study results suggested a relationship of the non-dipping BP pattern in GH with preterm delivery, birth weight, and maternal clinical findings.

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