• Saudi Med J · Aug 2022

    Review

    False-positive Xpert® Xpress SARS-CoV-2 assay in an emergency room and trauma center: A retrospective chart review study.

    • Hyerim Kim, Soeun Jeon, Sun Hack Lee, Hyun-Su Ri, Hyeon-Jeong Lee, Jeong-Min Hong, and Sung In Paek.
    • From the Department of Laboratory Medicine (Kim); from Biomedical Research Institute (Kim, Jeon, S. H. Lee, H-J. Lee, Hong); from the Department of Anesthesia and Pain Medicine (Jeon, H-J. Lee, Hong, Paek); from the Department of Internal Medicine (S. H. Lee), Division of Cardiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, and from the Department of Anesthesia and Pain Medicine (Ri), Kyungpook National University, School of Medicine, Daegu, Korea.
    • Saudi Med J. 2022 Aug 1; 43 (8): 965970965-970.

    ObjectivesTo review reports false-positive Xpert results in an emergency room and trauma center.MethodsPatients' data with false-positive Xpert results from November 2020 to February 2022 at Pusan National University Hospital, Busan, Republic of Korea, were extracted from the electronic medical records.ResultsThe positive predictive value of Xpert was 40%. Of the 12 patients with false-positive results, 5 (41.7%) were re-positives (such as, patients recovered from coronavirus disease-19 [COVID-19]), and 4 (33.3%) had head or facial trauma. Two out of 4 head or facial trauma cases had documented sample contamination with blood.ConclusionWe found a high incidence of false-positive Xpert results among patients who recovered from COVID-19 and those with head or facial injury. Careful history taking for COVID-19 and physical examination of the sample collection site is essential before Xpert analysis.Copyright: © Saudi Medical Journal.

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