• Austin C Cohrs, Diah E Husnul Khotimah, Andrew W Dick, Bradley D Stein, Rosalie Liccardo Pacula, Benjamin G Druss, Kyungha Kim, and Douglas L Leslie.
• Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, United States of America. Electronic address: acohrs@phs.psu.edu.
• Prev Med. 2022 Oct 1; 163: 107194107194.

AbstractLittle is known about the extent to which the prevalence of opioid-related problems (ORPs) varies among U.S. adolescents and young adults across geographic regions and over time, information that can help to guide policies that aim to curb the opioid epidemic. A retrospective, cross-sectional design was used to analyze longitudinal claims data from privately insured individuals aged 12-64 years who had an outpatient or inpatient diagnosis of an ORP in the years 2005-2018. The prevalence of opioid-related problem diagnoses (per 10,000) varied considerably across census divisions, both over time and between age groups. Knowledge of the origin of and variation in diagnosed opioid-related problems in terms of age group and census division is important so that interventions and policies can be more targeted and effective.Copyright © 2022 Elsevier Inc. All rights reserved.

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