• Seong-Hun Kim, Dae-Won Gwak, Jae-Gyeong Jeong, Hyunwoo Jung, Yu-Sun Min, Ae-Ryoung Kim, and Tae-Du Jung.
• Department of Rehabilitation Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea.
• Medicine (Baltimore). 2022 Aug 19; 101 (33): e29874e29874.

IntroductionCognitive dysfunction reduces patients' quality of life and social participation with traumatic brain injury (TBI). Computerized cognitive rehabilitation is increasingly being used for cognitive therapy in TBI patients. The purpose of this study was to investigate the influence of age on the effect of computerized cognitive rehabilitation in cognitive dysfunction after TBI.Material And MethodsA total of 34 patients with cognitive dysfunction after TBI were enrolled. Participants performed 30 sessions of computerized cognitive rehabilitation (Comcog) for 6 weeks. A cognitive evaluation was performed before and after treatment with Mini-Mental State Examination (MMSE) and Computerized Neurophyschologic Test (CNT).ResultsThere were no cognitive tests that differed between the young group and the old group at baseline. However, after computerized cognitive rehabilitation, the young group showed significant improvement compared to the old group in verbal memory, visual memory, attention, and visuo-motor coordination tests. The young group showed improvement in MMSE, verbal and visual memory, and visuo-motor coordination tests after computerized cognitive rehabilitation. In contrast, the old group showed significant improvement only in MMSE and visual learning test, one of the visual memory tests.ConclusionOur findings demonstrate that age may be an important factor related to the effect of computer cognitive rehabilitation on cognitive dysfunction after TBI. Methodologically more ordered studies with larger sample sizes are needed in the future.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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