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J Coll Physicians Surg Pak · Sep 2022
Case ReportsRole of Recombinant Activated Factor VIIa (rFVIIa) in Bleeding Mycotic Aneurysm of the Abdominal Aorta.
- Shaheen Bibi, Irfan Ahsan, Karimullah Makki, and Sidra Rauf.
- Department of Nephrology, Liaquat National Hospital, Karachi, Pakistan.
- J Coll Physicians Surg Pak. 2022 Sep 1; 32 (9): 1209-1211.
AbstractMycotic aortic aneurysm is an infective disease of the aorta with high mortality rate despite surgical repair. Recombinant activated factor VIIa (rFVIIa) is approved for the treatment of bleeding in hemophilia and used (off-labeled) in acute bleeding related to the trauma, cardiac surgery, and intracranial bleed. A 38-year female was admitted with abdominal pain, and was subsequently diagnosed with bleeding mycotic aneurysm of the abdominal aorta. She was given rFVIIa and the bleeding stopped successfully. We recommend further evaluation of the role of rFVIIa in bleeding mycotic abdominal aortic aneurysm, as it can bring a novel change in the management of this devastating disease. Key Words: Mycotic aortic aneurysm, Factor VIIa (rFVIIa), Abdominal aorta, Bleeding.
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