• Tohoku J. Exp. Med. · Oct 2022

    Case Reports

    Sjögren's Syndrome Presenting with Temporary Hemiplegia Mimicking Transient Ischemic Attack.

    • Yukiko Kamogawa, Kanae Akita, Hiroko Sato, Tsuyoshi Shirai, Tomonori Ishii, Hideo Harigae, and Hiroshi Fujii.
    • Department of Rheumatology, Tohoku University Hospital.
    • Tohoku J. Exp. Med. 2022 Oct 26; 258 (3): 207-211.

    AbstractSjögren's syndrome manifests with a wide variety of neurologic symptoms. This case report presents a 53-year-old woman with Sjögren's syndrome associated with temporal hemiplegia, which was suspected to be a transient ischemic attack. After induction of immunosuppressive therapies [high-dose prednisolone (1 mg/kg/day) and intravenous cyclophosphamide (total 5 g)], the hemiplegia did not reappear and the blood flow abnormalities remarkably improved as depicted on electroencephalography and single photon emission computed tomography. This case suggests that temporal hemiplegia presenting with transient ischemia-like attack symptoms may be a neurologic manifestation of Sjögren's syndrome and responsive to immunosuppressive therapy.

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