• Nutrition · Nov 2022

    Ultrasonografically assessed osteosarcopenic obesity is associated with frailty in community-dwelling older adults.

    • Arzu Okyar Baş, Merve Güner Oytun, Olgun Deniz, Yelda Öztürk, Zeynep Kahyaoğlu, Serdar Ceylan, Süheyla Çöteli, Ayşe Dikmeer, İbrahim İleri, Merve Hafızoğlu, Zeynep Şahiner, Burcu Balam Doğu, Mustafa Cankurtaran, and Meltem Gülhan Halil.
    • Hacettepe University, Department of Internal Medicine, Division of Geriatrics, Ankara, Turkey. Electronic address: arzu0506@hotmail.com.
    • Nutrition. 2022 Nov 1; 103-104: 111827111827.

    ObjectivesOsteosarcopenic obesity (OSO; also known as adiposity) is the combination of three critical conditions. This study aimed to define OSO using muscle ultrasonography (US), and examine the relationship between OSO and frailty compared with its constituent components.MethodsA total of160 geriatric patients with a body mass index of ≥30 were enrolled in the study. We obtained US measurements of the rectus femoris thickness and cross-sectional area (RFCSA). OSO was defined as the combination of low muscle function (defined by handgrip strength <27 kg in men and <16 kg in women), low muscle mass (RFCSA ≤5.22 cm2), and the clinical diagnosis of osteoporosis. The modified Fried Frailty Index and Clinical Frailty Scale were used to identify frailty.ResultsThe median age of participants was 72 y, and 83% (n = 137) were female. Patients were divided into four categories: Obese (n = 72; 43.6%), osteoporotic obese (n = 44; 26.7%), sarcopenic obese (n = 19; 11.5%), and osteosarcopenic obese (n = 25; 15.2%). In the subgroup analysis, the prevalence of frailty was significantly higher in the OSO group than in the other groups on both frailty scales (P < 0.05). The regression analysis showed that OSO significantly increased frailty status when adjusted for confounders detailed in Table 1 (Fried Frailty Index: odds ratio: 5.10; 95% confidence interval, 1.669-15.132; P = 0.004; Clinical Frailty Scale: odds ratio: 3.765; 95% confidence interval, 1.236-11.465; P = 0.020).ConclusionsUS-defined OSO is strongly associated with frailty in older adults according to the first study to define OSO using RFCSA measures.Copyright © 2022 Elsevier Inc. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…