• African health sciences · Aug 2022

    Makerere's contribution to the development of a high impact HIV research population-based cohort in the Rakai Region, Uganda.

    • Edward Nelson Kankaka, Fred Nalugoda, David Serwadda, Fredrick Makumbi, Maria J Wawer, Ronald H Gray, Thomas C Quinn, Steven J Reynolds, Gertrude Nakigozi, Tom Lutalo, Godfrey Kigozi, Nelson K Sewankambo, and Joseph Kagaayi.
    • Rakai Health Sciences Program.
    • Afr Health Sci. 2022 Aug 1; 22 (Spec Issue): 425042-50.

    AbstractLongitudinal population-based cohort studies can provide critical insights on temporal, spatial and sociodemographic changes in health status and health determinants that are not obtained by other study designs. However, establishing and maintaining such a cohort study can be challenging and expensive. Here, we describe the role of Makerere University in the development and conduct of such a cohort. We chronicle the first academia-led reports of HIV in East Africa; how this led to initiation of the Rakai Community Cohort Study in 1988, the first and oldest HIV cohort in sub-Saharan Africa; its impact on HIV prevention, care and treatment; how the cohort has been maintained; and opportunities, challenges, and future directions including non-communicable diseases.© 2022 Kankaka EN et al.

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