• Mayo Clinic proceedings · Nov 2022

    Association of Lifestyle Behaviors With Hearing Loss: The UK Biobank Cohort Study.

    • Humberto Yévenes-Briones, Francisco Félix Caballero, José Ramón Banegas, Fernando Rodríguez-Artalejo, and Esther Lopez-Garcia.
    • Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid and CIBERESP (CIBER of Epidemiology and Public Health), Madrid, Spain. Electronic address: humbertoyevenesbriones@gmail.com.
    • Mayo Clin. Proc. 2022 Nov 1; 97 (11): 204020492040-2049.

    ObjectiveTo examine the combined association of five healthy lifestyle behaviors with hearing loss (HL) in the UK Biobank cohort, established between 2006 and 2010 in the United Kingdom.MethodsThis longitudinal analysis included 61,958 participants aged 40 to 70 years from April 2007 to December 2016. The healthy behaviors examined were: never smoking, high level of physical activity, high diet quality, moderate alcohol intake, and optimal sleep. Hearing loss was self-reported at baseline and in any physical exam during the follow-up.ResultsOver a median follow-up of 3.9±2.5 years, 3072 (5.0%) participants reported incident HL. After adjustment for potential confounders, including age, social factors, exposure to high-intensity noise, ototoxic medication, and comorbidity, the HRs of HL associated with having 1, 2, 3, and 4 to 5 vs 0 behaviors were: 0.85 (95% CI, 0.75 to 0.96), 0.85 (95% CI, 0.75 to 0.96), 0.82 (95% CI, 0.71 to 0.94), and 0.80 (95% CI, 0.67 to 0.97), respectively (P for trend, 0.02). We estimated that the population attributable risk percent for not adhering to any five low-risk lifestyle behaviors was 15.6%.ConclusionIn this large study, an increasing number of healthy behaviors was associated with decreased risk of HL.Copyright © 2022 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

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