• So Hee Kim, Hyung Joon Yoon, Nam Kyung Lee, Kyung Un Choi, Ki Hyung Kim, and Dong Soo Suh.
• Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Pusan National University School of Medicine, Busan, Republic of Korea.
• Medicine (Baltimore). 2022 Nov 11; 101 (45): e31579e31579.

IntroductionA poorly differentiated lymphoepithelioma-like carcinoma (LELC) of the cervix is an extremely rare presentation. We herein present an unusual case of LELC of the cervix, which was treated with radical trachelectomy for fertility preservation.Patient ConcernsA 28-year-old female patient presented with a 1-month-history of post-coital vaginal bleeding, and a 2 cm tumor was found on gynecological sonography and magnetic resonance imaging.DiagnosisThe final pathological examination established a conclusive diagnosis of LELC of the cervix. After surgery, the patient was finally diagnosed as The International Federation of Gynecology and Obstetrics (FIGO) stage IB1 with no vaginal wall or parametrium infiltration.InterventionsSubsequently, a surgery was scheduled, and intraoperatively, we performed resection twice because of a frozen biopsy result that was resection margin-positive initially. As a result, further resection was performed, which was a 5mm thickness for each. Cisplatin adjuvant chemotherapy was administered 3 weeks after the operation to prevent recurrence.OutcomesThe patient has been followed for 1 year postoperatively, with an adjuvant treatment, with no evidence of tumor recurrence or metastasis.ConclusionBased on this case, we highly recommend that operators should consider a deeper resection margin range than that visible on magnetic resonance imaging. More attention is needed to better understand the treatment method for LELC of the cervix. We also plan to closely monitor the patient's prognosis and fertility, and to conduct additional studies.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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