• Jie Men, Wenjuan Wang, Jian Zhao, Jie Wen, Qingqing Hao, Shufeng Li, and Shuangling Zou.
• Department of Medical Laboratory Science, Fengyang College, Shanxi Medical University, Shanxi, China.
• Medicine (Baltimore). 2022 Nov 11; 101 (45): e31861e31861.

ObjectivesThis study aimed to explore the relationship between exercise and cerebral stroke and provide evidence for the prevention of cerebral stroke.Materials/MethodsAll clinical trials of exercise intervention for atherosclerosis were systematically reviewed. Five major databases were searched to retrieve relevant studies from their inception to May 2022. According to the magnitude of heterogeneity, the random and fixed-effect models were used to test reasonably.ResultsAccording to the inclusion and exclusion criteria, 1341 articles were screened and 13 articles involving 825 patients were identified. The result showed that in the randomized controlled trials carotid intima-media thickness index was lower in the exercise group (-0.04 mm, 95% confidence interval: -0.07 to -0.01). All were statistically significant (P < .005) and subgroup analysis showed that the intervention period and paper quality are sources of heterogeneity.ConclusionsThe results of this systematic review suggest that exercise is associated with a slow increase in carotid intima-media thickness, which may provide evidence that exercise helps reduce cerebral stroke.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

9 keywords...

hide…