• Fatih Aksoy, Hasan Aydin Baş, Ali Bağcı, Hasan Basri Savaş, and Mehmet Özaydın.
• Suleyman Demirel University, Medical School, Department of Cardiology - Isparta, Turkey.
• Rev Assoc Med Bras (1992). 2022 Jan 1; 68 (10): 136913751369-1375.

ObjectiveThis study aimed to evaluate the association between left ventricular ejection fraction recovery and the total oxidant status, total antioxidant capacity, and high-sensitivity C-reactive protein levels.MethodsA total of 264 ST-elevation myocardial infarction patients were classified into two groups according to baseline and 6-month follow-up left ventricular systolic function: reduced and recovery systolic function. Predictors of the recovery of left ventricular ejection fraction were determined by multivariate regression analyses.ResultsMultivariable analysis indicated that oxidative status index, baseline left ventricular ejection fraction and peak creatine-kinase myocardial bundle level, and high-sensitivity C-reactive protein were independently associated with the decreased of left ventricular ejection fraction at 6-month follow-up.ConclusionOxidative stress and inflammation parameters were detrimental to the recovery of left ventricular ejection fraction in patients with ST-elevation myocardial infarction.

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