• P L Steer and H B Krantz.
• Department of Anesthesiology, University of Kansas Medical Center, Kansas City 66160-7415.
• J Clin Anesth. 1993 Sep 1;5(5):419-24.

Study ObjectiveTo compare values for two whole blood viscoelastic coagulation tests, thromboelastography (TEG) and Sonoclot analysis (Sonoclot R Coagulation Analyzer, Sienco, Inc., Morrison, CO), between healthy parturients and nonparturients.DesignProspective study.SettingUniversity hospital.Patients41 healthy, nonpregnant females and full-term nonlaboring and laboring parturients.InterventionsBlood samples for TEG and Sonoclot analysis were taken from all patients. TEG tracings were analyzed for reaction time (R), coagulation time (RK), the difference between RK and R (K), clot formation rate (alpha degree), and maximum amplitude (MA) values. Sonoclot tracings were analyzed for onset, rate increases, peak, and rate decreases values.Measurements And Main ResultsAll TEG values were significantly different between nonpregnant females and parturients (p < 0.05). Sonoclot analysis showed that the parturients had a significantly decreased onset and increased primary slope (rate increases) in comparison to the nonpregnant females (p < 0.05).ConclusionThe differences found in the parturients reflect a hypercoagulable state. If these tests are to be used in evaluating obstetric patients, the results should be compared with values obtained for healthy parturients, not healthy nonparturients.

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