• Margaret Veitch, Craig Layt, Emma Raymond, Andrew J Croaker, and James W Wells.
• The University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Brisbane, Australia.
• Arch Med Sci. 2022 Jan 1; 18 (6): 168316881683-1688.

IntroductionThe objective of the study was to characterize the baseline intra-individual and inter-individual variability of immune cell subsets within abdominoplasty skin specimens.MethodsAbdominoplasty biopsies were taken from 5 patients and analysed using the Vectra 3 automated quantitative pathology imaging system with inForm software.ResultsAdjacent skin regions demonstrated intra-patient variability in immune subset counts ranging from 1- to 5-fold. Inter-variability between patients was approximately 2- to 7-fold for most subsets, except for HLA-DR+ antigen presenting cells, which varied 19-fold.ConclusionsOur data highlight the importance of including multiple patients and multiple patient samples when designing dermatological studies that utilise abdominoplasty skin.Copyright: © 2022 Termedia & Banach.

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