• Jin-Ho Jeong and Ji Hye Hwang.
• Namsangcheon Korean Medicine Clinic, Seoul, Republic of Korea.
• Medicine (Baltimore). 2022 Nov 25; 101 (47): e31458e31458.

BackgroundNerve entrapment syndrome occurs when the nerves become compressed or entrapped and restricted. This study aims to evaluate the effectiveness and safety of pharmacopuncture in patients with nerve entrapment syndrome.MethodsA search will be conducted from inception to August 2022 using the following 11 electronic databases: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine Database China National Knowledge Infrastructure, and 6 Korean databases. All randomized controlled trials (RCTs) evaluating pharmacopuncture treatment for various nerve entrapment syndromes will be considered, with no restrictions regarding the type of pharmacopuncture solution used. Two reviewers will perform the data extraction and quality assessment using a predefined data extraction form. The methodological quality of the included RCTs will be assessed using the Cochrane risk-of-bias tool.ResultsThis systematic review will provide high-quality evidence to determine the efficacy and safety of pharmacopuncture therapy for nerve entrapment syndrome.ConclusionOur findings will be informative for patients with nerve entrapment syndrome, as well as clinicians, policymakers, and researchers.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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