• Felipe Mendes Delpino, Lílian Munhoz Figueiredo, Thaynã Ramos Flores, Erika Aparecida Silveira, Francine Silva Dos Santos, André Oliveira Werneck, Maria Laura da Costa Louzada, Ricardo Alexandre Arcêncio, and Bruno Pereira Nunes.
• Postgraduate Program in Nursing, Federal University of Pelotas, Pelotas, Brazil; University of São Paulo, São Paulo, Brazil. Electronic address: fmdsocial@outlook.com.
• Nutrition. 2023 Feb 1; 106: 111908111908.

AbstractThe aim of this review article was to evaluate the association between the intake of ultra-processed foods and sleep-related outcomes through a systematic review and meta-analysis. Pubmed, LILACS, Scielo, Scopus, Embase, and Web of Science were searched on December 31, 2021, for studies that evaluated the association between ultra-processed foods and sleep-related outcomes (self-reported sleep duration and quality). Pooled odds ratios were assessed through a random-effects model; heterogeneity was evaluated using the I2 statistic. Fifteen cross-sectional studies were included; 14 showed that the high intake of ultra-processed foods was statistically significantly associated with sleep-related outcomes (sleep duration and quality). In the crude analysis, compared with low intake, high intake of ultra-processed foods increased the odds of sleep-related outcomes, with increased odds among children and/or adolescents, and null results among adults. When adjusted for cofounders, we found statistically significant results for all ages. The high intake of ultra-processed foods was associated with sleep-related outcomes, with moderate credibility of the evidence. Longitudinal studies and clinical trials confirming these findings are necessary.Copyright © 2022 Elsevier Inc. All rights reserved.

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