• Soo Kyoung Kim, Bo Ra Kim, Kyongyoung Kim, Sungsu Kim, Jung Hwa Jung, Jong Ryeal Hahm, and Jaehoon Jung.
• Department of Internal Medicine, Gyeongsang National University School of Medicine, South Korea.
• Intern. Med. 2015 Jan 1; 54 (19): 247124742471-4.

AbstractEndocrine diseases are frequently accompanied by diabetes mellitus and treatment of an underlying endocrine disease often improves glucose control. The co-occurrence of acromegaly and Cushing's syndrome is extremely rare. We herein describe a patient who showed a dramatic improvement in glucose control following treatment for co-existing acromegaly and Cushing's syndrome. An adrenal mass was incidentally discovered during a routine evaluation of a 56-year-old woman who was subsequently diagnosed with acromegaly and a unilateral cortisol-producing adrenal adenoma. Her blood glucose was poorly controlled despite receiving high-dose insulin therapy. After undergoing adrenalectomy for Cushing's syndrome, her insulin dosage was decreased by almost 50%. The insulin treatment was discontinued following the treatment of acromegaly.

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