-
African health sciences · Dec 2014
Serum HE4 is more suitable as a biomarker than CA125 in Chinese women with benign gynecologic disorders.
- Yan Zhang, Chunxia Qiao, Lian Li, Xuye Zhao, and Yali Li.
- Department of Gynecology and Obstetrics, the Chinese PLA General Hospital.
- Afr Health Sci. 2014 Dec 1; 14 (4): 913918913-8.
ObjectiveThis study measured the human epididymis protein 4 (HE4) and CA125 levels in Chinese women with benign gynecological disorders.Material And MethodsSera were obtained from Chinese women prior to surgery for a pelvic mass and HE4 and CA125 levels were determined. The proportions of patients with HE4 and CA125 levels were compared.ResultsThere were 68 Chinese women with benign diseases. HE4 levels were less elevated than CA125 (1% V.S. 29%, P<0.001). The significant difference was observed in patients with endometriosis/endometriomas in which HE4 was not elevated patients and CA125 was elevated in 53% (P<0.001). Serum HE4 level was not elevated in patients with cystadenoma (0% V.S. 23%, P<0.001) and in patients with germ cell tumors (0% V.S. 5%, P<0.001).ConclusionHE4 was less elevated and more suitable as a biomarker than CA125 in chinese women with benign disease.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..