• Internal medicine · Jan 2015

    Case Reports

    Non-occlusive mesenteric ischemia after splenic metastasectomy for small-cell lung cancer.

    • Hiromichi Yamane, Naoki Fukuda, Ken Nishino, Kazuhiro Yoshida, Nobuaki Ochi, Tomoko Yamagishi, Yoshihiro Honda, Hirofumi Kawamoto, Yasumasa Monobe, Hidefumi Mimura, Yoshio Naomoto, and Nagio Takigawa.
    • Department of General Internal Medicine 4, Kawasaki Medical School, Japan.
    • Intern. Med. 2015 Jan 1; 54 (7): 743747743-7.

    AbstractA 68-year-old man presented with severe abdominal pain. Seven months earlier, he had received systemic chemotherapy for small-cell lung cancer with solitary metastasis to the spleen, followed by splenectomy. Abdominal computed tomography and abdominal arterial angiography showed diffuse ischemia of the mesenteric artery without apparent occlusion. The patient also suffered from septicemia caused by Enterococcus faecium. Therefore, a diagnosis of non-occlusive mesenteric ischemia (NOMI) induced by septicemia was supposed. Although treatment with antibiotics and papaverine hydrochloride was administered and the necrotic tissue in the intestinal tract was resected, the patient died. Physicians should be aware that patients undergoing splenectomy are likely to be affected by septicemia, which may subsequently induce NOMI.

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