• Medicine · Dec 2022

    Review

    The potential of articaine as new generation of local anesthesia in dental clinics: A review.

    • Wen Luo, Kaiyue Zheng, Huifang Kuang, Zhixin Li, Jinrong Wang, and Jie Mei.
    • Department of Stomatology, the First Affiliated Hospital of Hainan Medical University, Haikou, China.
    • Medicine (Baltimore). 2022 Dec 2; 101 (48): e32089e32089.

    AbstractAs a new drug for local dental anesthesia, articaine has become popular in the clinic in recent years. In this review, we describe the development of articaine, explain its mechanism of action, compare its efficacy with that of other commonly used local anesthetics in dental treatment, and summarize the application of articaine in special populations. In conclusion, the anesthetic efficacy of articaine in clinical dental treatment is better than that of lidocaine, and its safety is not statistically different from that of lidocaine. In particular, articaine has several advantages and can be selected flexibly for clinical use. Atecaine has great potential for wide application in dental clinics in the near future.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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