• Yuancheng Gao, Yue Ji, Yulin Song, Rui Gong, Cheng Chen, and Hongbo Chen.
• Zhejiang Chinese Medical University, Hangzhou, China.
• Medicine (Baltimore). 2022 Dec 2; 101 (48): e32034e32034.

BackgroundType 2 diabetic kidney disease (DKD) is one of the most common and harmful chronic complications in clinical practice, and there is no reliable and targeted treatment plan at present. As a classic complementary and alternative therapy, evidence have shown that warm acupuncture has advantages in the treatment of type 2 DKD. However, there is still a lack of high-quality and long-term follow-up randomized controlled trials of warm acupuncture in the treatment of type 2 DKD.MethodsThis is a prospective randomized controlled trial to investigate the efficacy and safety of warm acupuncture in the treatment of type 2 DKD. Participants will be randomly assigned in a 1:1 ratio to either the treatment group (treated with conventional Western medicine) or the control group (treated with warm acupuncture added on the basis of the control group). Both groups will receive 12 weeks of treatment followed by 24 weeks of follow-up. Observation indicators include: 24-hour urinary protein quantification, kidney function, TCM syndrome score and adverse reactions. Finally, SPSS21.0 software will be used to analyze the data.DiscussionThis study will evaluate the efficacy and safety of warm acupuncture in the treatment of DKD, and the results of this trial will provide clinical evidence for the treatment of type 2 DKD.Trial RegistrationThe TCTR identification number is TCTR20221104004.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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