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Case Reports
Positive response of a recurrent clear cell sarcoma to anlotinib combined with chemotherapy: A case report.
- Junyue Tao, Hao Yang, Zongyao Hao, Chaozhao Liang, Yingying Du, Chao Zhang, Yu Yin, and Jun Zhou.
- Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China.
- Medicine (Baltimore). 2022 Dec 2; 101 (48): e32109e32109.
RationaleRenal clear cell sarcoma is a rare and highly invasive malignant renal tumor that easily relapses after treatment. Recurrent recurrent clear cell carcinoma (CCSK) responds poorly to chemotherapy and has no established standardized treatment, and need to be explored potentially useful treatments.Patient ConcernsA 18-years-old patient with renal clear cell sarcoma recurrence after open radical nephrectomy.DiagnosisRecurrent clear cell sarcoma.InterventionsAfter chemotherapy alone failed, the patient received 6 courses of anlotinib combined with chemotherapy. The tumor had significantly reduced in size and the recurrent tumor and part of the liver were resected.OutcomesNo tumor recurrence or metastasis was detected during the follow-up 8 months after the operation.LessonsThis is the first report describing the use of anlotinib in treating CCSK. We believe that anlotinib combined with chemotherapy may be a useful treatment option for patients with recurrent CCSK.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.
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