• F Piñeiro Chousa, V F Gil Guillén, M Donis Otero, D Orozco Beltrán, R Pastor López, and J Merino Sánchez.
• Departamento de Medicina, Universidad de Alicante.
• Rev Clin Esp. 1997 Aug 1; 197 (8): 555559555-9.

ObjectivesTo validate six indirect methods for evaluation of therapy compliance with oral hypoglycemic agents: self-reported compliance, attendance to scheduled visits, Morisky-Green test, degree of disease control, medical judgement and level of knowledge on the disease.Patients And MethodsThe certainty method used was pill counts at patient's home by surprise with a sample of 107 randomly selected patients from three Primary Care Centers in the province of Alicante.ResultsSV was the method with the highest specificity (94.2%), likelihood of low compliance (84.2%) and percentage of likelihood of low compliance (5.1). DC assessed by basal blood glucose had the highest sensitivity (81.8%) and DC assessed by glycoxylated hemoglobin the highest likelihood of high compliance (61.1%).ConclusionsIn this study, SV and DC with basal blood glucose were the highest validity indicators and could be used combined in clinical practice to evaluate compliance with oral hypoglycemic agents.

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