• Carolina Hanna Chaim, Erica Rosanna Siu, Carlos Felipe Cavalcanti Carvalho, Fernanda Piotto Frallonardo, Flavia Ismael, AndradeArthur Guerra deAG0000-0002-6856-8212MD, PhD. Associate Professor, Department of Psychiatry, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo (SP), and Full Professor, ABC Center for Mental Health Studies, Department of Neurosc, Antonio Ventriglio, Julio Torales, Dinesh Bhugra, and João Mauricio Castaldelli-Maia.
• MD. Research Associate, Department of Psychiatry, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo (SP), Brazil.
• Sao Paulo Med J. 2019 Jul 29; 137 (3): 234240234-240.

BackgroundThere are still few studies on predictors of smoking cessation in Brazilian samples. Experimentation with tobacco during adolescence (ETA) may be one of the important predictors.ObjectiveThis study aimed, within the context of a treatment-seeking group of subjects, to test the hypothesis that ETA negatively affects the outcome of smoking cessation during adulthood.Design And SettingRetrospective (historic) cohort study conducted at a psychosocial care center in São Paulo, Brazil, between 2007 and 2010.MethodsData on sociodemographics, smoking and medical profiles were obtained through self-report questionnaires that were completed at the baseline and at any follow-up appointment. Logistic regression models were constructed to describe factors associated with the outcome of smoking cessation, measured according to the self-reported four-week success rate among 367 outpatient smokers.ResultsETA was found to be associated with not quitting smoking through the treatment (odds ratio = 0.57; 95% confidence interval = 0.33-0.96; P < 0.05), even after adjustment for dependence level, sociodemographics, nicotine patch use and number of years of smoking.ConclusionsEarly exposure to nicotine may lead to higher risk of continuing smoking after treatment, in adulthood.

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