• Lin Wang, Bugao Guan, Guangrun Li, Liquan Feng, Hui Sun, and Jin Xu.
• Department of Rehabilitation Medicine, Jinhu County People's Hospital, Huai'an, Jiangsu Province, China.
• Medicine (Baltimore). 2022 Dec 16; 101 (50): e31467e31467.

BackgroundThe efficacy and safety of traditional Chinese medicine physiotherapy combined with acupoint injection in treating diabetic peripheral neuropathy remains unknown. As a result, we will conduct a systematic review and meta-analysis to assess the evidence.MethodsWe will look for pertinent randomized controlled trials in the following databases: China National Knowledge Infrastructure, WanFangData, Chinese biological medical database, Medline, Cochrane Library, PubMed, and Embase up to January 2022. Following the standards of Cochrane Review 6.2, 2 researchers independently evaluated the quality of the evidence in the relevant papers. Data analysis will be conducted by using Review Manager 5.4, including statistical analysis, subgroup analysis, making forest plot and funnel chart.ResultsThe results will be submitted to a peer-reviewed journal.ConclusionThe research will verify the safety and efficacy of traditional Chinese medicine physiotherapy in combination with acupoint injection for diabetic peripheral neuropathy.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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