• Medicine · Dec 2022

    Anxiety and depression among pregnant women undergoing IVF-ET and WeChat group peer support during the COVID-19 pandemic: Study protocol for a randomized controlled trial.

    • Jing-Xian Cao, Wen-Jing Jiang, Meng-Han Yan, Dan-Dan Wang, Jin-Wei Hou, Jing-Yan Song, and Zhen-Gao Sun.
    • The First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
    • Medicine (Baltimore). 2022 Dec 23; 101 (51): e32515e32515.

    IntroductionThe psychological well-being of pregnant women following assisted reproductive has increasingly gained attention in recent years. Anxiety and depression may be associated to pregnancy outcomes. This study aims to determine whether peer support and the WeChat group platform will reduce anxiety and depression among in vitro fertilization and embryo transfer (IVF-ET) women.Methods And AnalysisIn the present randomized controlled study, 296 patients with confirmed clinical pregnancy following IVF-ET will be randomly assigned to receive standard intervention support or WeChat peer support on a 1:1 basis. The levels of anxiety and depression are the primary endpoints. Assessments will be performed at baseline measurements, first trimester, second trimester, and third trimester, and data will be collected.Ethics And DisseminationThis study has been approved as ethical by the affiliated hospital of Shandong University of Traditional Chinese Medicine's Reproductive Ethics Committee. Each patient will sign a written statement of informed permission. All information and biological samples will be legally protected. A peer-reviewed academic journal will publish the findings of this investigation.DiscussionGiven the inconvenience of visits due to the current pandemic of COVID-19, this study addresses the patient's visit needs by combining WeChat, the most widely used social software in China, with peer support, while helping improve maternal anxiety, depression, and pregnancy outcomes following IVF-ET.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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