• Medicine · Dec 2022

    Multicenter Study

    Effect of low body mass index on clinical recovery after fusion surgery for osteoporotic vertebral fracture: A retrospective, multicenter study of 237 cases.

    • Gen Inoue, Masayuki Miyagi, Wataru Saito, Eiki Shirasawa, Kentaro Uchida, Naobumi Hosogane, Kei Watanabe, Keiichi Katsumi, Takashi Kaito, Tomoya Yamashita, Hiroyasu Fujiwara, Yukitaka Nagamoto, Kenya Nojiri, Satoshi Suzuki, Eijiro Okada, Seiji Ueda, Tomohiro Hikata, Yuta Shiono, Kota Watanabe, Hidetomi Terai, Koji Tamai, Yuji Matsuoka, Hidekazu Suzuki, Hirosuke Nishimura, Atsushi Tagami, Shuta Yamada, Shinji Adachi, Seiji Ohtori, Takeo Furuya, Sumihisa Orita, Kazuhide Inage, Toshitaka Yoshii, Shuta Ushio, Haruki Funao, Norihiro Isogai, Katsumi Harimaya, Seiji Okada, Kenichi Kawaguchi, Nobuhiko Yokoyama, Hidekazu Oishi, Toshio Doi, Katsuhito Kiyasu, Shiro Imagama, Kei Ando, Kazuyoshi Kobayashi, Daisuke Sakai, Masahiro Tanaka, Atsushi Kimura, Hirokazu Inoue, Atsushi Nakano, Shota Ikegami, Masayuki Shimizu, Toshimasa Futatsugi, Kenichiro Kakutani, Takashi Yurube, Kazuyoshi Nakanishi, Masashi Oshima, Hiroshi Uei, Yasuchika Aoki, Masahiko Takahata, Akira Iwata, Hirooki Endo, Shoji Seki, Hideki Murakami, Satoshi Kato, Katsuhito Yoshioka, Michio Hongo, Tetsuya Abe, Toshinori Tsukanishi, Masashi Takaso, and Ken Ishii.
    • Department of Orthopaedic Surgery, Kitasato University, Sagamihara City, Kanagawa, Japan.
    • Medicine (Baltimore). 2022 Dec 30; 101 (52): e32330e32330.

    AbstractA retrospective multicenter study. Body mass index (BMI) is recognized as an important determinant of osteoporosis and spinal postoperative outcomes; however, the specific impact of BMI on surgery for osteoporotic vertebral fractures (OVFs) remains inconclusive. This retrospective multicenter study investigated the impact of BMI on clinical outcomes following fusion surgery for OVFs. 237 OVF patients (mean age, 74.3 years; 48 men and 189 women) with neurological symptoms who underwent spinal fusion were included in this study. Patients were grouped by World Health Organization BMI categories: low BMI (<18.5 kg/m2), normal BMI (≥18.5 and <25 kg/m2), and high BMI (≥25 kg/m2). Patients' backgrounds, surgical method, radiological findings, pain measurements, activities of daily living (ADL), and postoperative complications were compared after a mean follow-up period of 4 years. As results, the proportion of patients able to walk independently was significantly smaller in the low BMI group (75.0%) compared with the normal BMI group (89.9%; P = .01) and the high BMI group (94.3%; P = .04). Improvement in the visual analogue scale for leg pain was significantly less in the low BMI group than the high BMI group (26.7 vs 42.8 mm; P = .046). Radiological evaluation, the Frankel classification, and postoperative complications were not significantly different among all 3 groups. Improvement of pain intensity and ADL in the high BMI group was equivalent or non-significantly better for some outcome measures compared with the normal BMI group. Leg pain and independent walking ability after fusion surgery for patients with OVFs improved less in the low versus the high BMI group. Surgeons may want to carefully evaluate at risk low BMI patients before fusion surgery for OVF because poor clinical results may occur.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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